Vis bubble5/20/2023 According to the Dry Eye Workshop 1 the two core mechanisms of dry eye are “tear film instability” and “tear hyperosmolarity.” Tear film instability is recorded as the time for “breakup” to occur after a blink, either by instilling fluorescein and observing the first dark spot in the fluorescent image 2 or by noninvasive observation of distortion/disruption of the tear film surface.
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